Rationally designed PPARδ-specific agonists and their therapeutic potential for metabolic syndrome
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چکیده
منابع مشابه
Rationally designed PPARδ-specific agonists and their therapeutic potential for metabolic syndrome.
The peroxisome proliferator-activated receptor (PPAR) family of nuclear receptors regulates a wide variety of lipid-related genes, including those responsible for adipose differentiation, cholesterol metabolism, and lipidmetabolism and transport. There are three different PPAR nuclear receptors, with different localizations and specializations. PPARα is primarily expressed in the liver, heart, ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2017
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1702084114